INTER AND INTRAPATIENT EVOLUTION OF HEPATITIS C VIRUS

Inter and intrapatient evolution of hepatitis C virus

Hepatitis C virus (HCV) has a short replication time, high mutation rates and large population sizes, all of which make it an excellent experimental model for evolution studies, because evolution can be visualized in real-time.In this review, we discuss the implications to study HCV evolution at the interpatient and intrapatient levels of infection

read more

Isolation, Genomic Analysis, and Preliminary Application of a Bovine Klebsiella pneumoniae Bacteriophage vB_Kpn_B01

Klebsiella pneumoniae is an important pathogen that can infect both humans and cattle.The widespread K.pneumoniae and its high drug resistance make it difficult to treat Klebsiella infections/diseases.In this study, a lytic K.pneumoniae bacteriophage vB_Kpn_B01 was isolated from a dairy farm trough in Sichuan Province, and its biological properties

read more

On Data Space Selection and Data Processing for Parameter Identification in a Reaction-Diffusion Model Based on FRAP Experiments

Fluorescence recovery after photobleaching (FRAP) is a widely used measurement technique to determine the mobility of fluorescent molecules within living cells.While the experimental setup and protocol for FRAP experiments are usually fixed, data (pre)processing represents an important issue.The aim of this paper is twofold.First, we formulate and

read more